Hyperuricosuria (HUU) means elevated levels of uric acid in the urine. This trait predisposes dogs to form stones in their bladders or sometimes kidneys. These stones often must be removed surgically and can be difficult to treat. HUU is inherited as a simple autosomal recessive defect.
The HUU test has been available to our breed only for a short time. We recommend that dogs tested as ‘carriers’ of the HUU gene may only be bred to ‘normal” tested dogs. The goal should be to eliminate this severe genetic disorder in the breed over the years. Therefore, we highly recommend that breeders choosing to breed a ‘carrier’ carefully look at the overall qualities of the dog and breed with the goal of eliminating ‘carriers’ from breeding programs. HUU carriers should never be frequently used in breeding programs and breeders that mate a carrier should test their puppies before they make a decision on selling with a breeding contract.